EUROTOX 08.-11.September 2024, Copenhagen, Denmark
Xiao-Yann Huang, Jimmy Vernaz, Song Huang and Samuel Constant
Epithelix Sàrl, 18 chemin des Aulx, CH-1228 Plan-les-Ouates, Geneva, Switzerland
Introduction
When the nasal cavities do not contain enough moisture, dry nose symptoms can manifest such as pain and swelling, nosebleeds, and even airway infections. Nasal dryness can often degrade the quality of life, therefore, novel topical treatments formulated as nasal sprays are needed to treat the severe cases. To test simultaneously efficacy and toxicity effect of novel formulations, we developed an in vitro “Dry Nose” model based on a fully differentiated human nasal epithelium cultured at the air-liquid interface.
