News & Publications

July 2, 2024

Product News 06/2024

See our new VITROCELL Essentials. Simplifying in vitro exposures with essential functionality. Welcome to the world of Vitrocell Essentials – […]

June 27, 2024

VITROCELL at the SOT – Society of Toxicology’s 64th Annual Meeting and ToxExpo, March 16th – 20th 2025, Orlando, Florida (USA)

Escape to Warm Weather with SOT The SOT 64th Annual Meeting and ToxExpo will feature five days of Featured and […]

June 21, 2024

New Air-Liquid Interface Products at VITROCELL User Group Meeting 2024

Intensive experience exchange in Nice / France on 19 June 2024 We had an excellent meeting with our customers – […]

June 10, 2024

Aerosol Exposure at the Air-Liquid Interface of Human Lung Organotypic Cultures using VITROCELL™ Continuous Flow Inhalation System

MPS World Summit 2024, June 10 – June 14, Seattle, Washington Joanne Wallace, Taseef Khalid, Kamil Czuchrowski, Stephen Huish, Iain […]

May 17, 2024

Did you know about FAT and SAT?

At VITROCELL, we are committed to delivering not just exceptional product quality and reliability but also an outstanding customer experience. […]

May 14, 2024

Important Request for Information (RFI) – National Institute of Environmental Health Sciences (NIEHS), feedback should be provided by June 7, 2024

We wish to draw your attention on the following RFI issued by the Occupational and Inhalation Exposures (OIE) Program within […]

April 11, 2024

In vitro toxicological evaluation of glo menthol and non-menthol heated tobacco products

DOI: 10.1016/j.tox.2024.153801 Brian M. Keyser, Robert Leverette, Reagan McRae, John Wertman, Tom Shutsky, Kristen Jordan , Ken Szeliga , Patrudu MakenaRAI […]

April 9, 2024

Invitation: 2024 User Group Meeting

(VITROCELL customers only) We wish to invite our customers to participate in our User Group Meeting 2024, an excellent opportunity […]

April 2, 2024

VITROCELL at the SOT – Society of Toxicology’s 63rd Annual Meeting and ToxExpo, March 11th – 13th 2024, Salt Lake City, Utah (USA)

++++++++++ REVIEW: We thank all our visitors at the VITROCELL booth for their interest in the new VITROCELL products! It […]

March 12, 2024

Evaluation of respiratory toxicity induced by didecyldimethylammonium chloride aerosol

Poster, SOT 63rd Annual Meeting and ToxExpo, March 10–14, 2024, Salt Lake City, Utah. Jun Woo Kim1, Ga Eun Kim2, […]

March 12, 2024

Positive controls use for performance evaluation of an in vitro test system designed for the prediction of chemical respiratory sensitizers

Poster, SOT 63rd Annual Meeting and ToxExpo, March 10–14, 2024, Salt Lake City, Utah. Sabina Burla1,2, Aline Chary1, Pamina Weber1, […]

March 12, 2024

In Vitro Evaluation of Inhalation Toxicity Induced by 2,3-Pentanedione Vapor Using a VITROCELL 48 2.0 Plus Exposure System and Air-Liquid Interface (ALI) Airway Model

Poster, SOT 63rd Annual Meeting and ToxExpo, March 10–14, 2024, Salt Lake City, Utah. WM Gwinn1, GK Roberts1, P-L Yao1, […]

March 12, 2024

The INSPIRE Initiative: Using human cell-based in vitro systems to assess respiratory toxicity of surfactants delivered as liquid or aerosols

Poster, SOT 63rd Annual Meeting and ToxExpo, March 10–14, 2024, Salt Lake City, Utah. Monita Sharma1, Andreas O. Stucki1, Sandra […]

March 11, 2024

Investigation on the biological effects of 3D reconstructed human airway tissue exposed at the air-liquid interface to aerosols generated from waterpipe tobacco blends with varying concentrations of cinnamaldehyde

Poster, SOT 63rd Annual Meeting and ToxExpo, March 10–14, 2024, Salt Lake City, Utah. Jeremie Gafner , Christelle Lamboley , […]

March 9, 2024

Meet VITROCELL at SOT in Salt Lake City, Utah during March 11-13, 2024

We kindly invite you to visit us in the exhibition area at booth #912 to discuss our in vitro exposure […]

March 7, 2024

Product News 03/2024

One of our brand new product developments: VITROCELL® AirTox Monitor for highest automation an reproducibility. We have some exciting new […]

March 5, 2024

VITROCELL at the 58th Congress of the European Societies of Toxicology (EUROTOX), September 08-11, 2024

Meet us at the #Booth 54. VITROCELL will participate in the EUROTOX, September 08-11, 2024 at Copenhagen, Denmark. The Danish […]

March 5, 2024

VITROCELL at the AEROSOLS AND MICROBIOLOGY, June 04-06, 2024 at Bristol, United Kingdom

+++++++++ REVIEW: We participated for the first time in this specialized international conference focused on aerosols and microbiology. In the […]

March 4, 2024

VITROCELL at the 3rd MPS World Summit, June 10-14, 2024 at Seattle, Washington

+++++++ REVIEW from the 3rd Microphysiological Systems World Summit (MPS World Summit) In all talks and discussions, the participants showed […]

March 4, 2024

VITROCELL at the ESTIV 2024 – International Congress of the European Society of Toxicology In Vitro, June 3-6, 2024 at Prague, Czech Republic

+++++++ REVIEW: European Society of Toxicology in Vitro ESTIV 2024 in Prague was a wonderful opportunity to reconnect with old […]

February 26, 2024

In Vitro Inhalation Toxicology at the 2023 DDL Conference

We’re excited to share an insightful and very comprehensive talk by Victoria Hutter on in vitro inhalation toxicology from the […]

February 14, 2024

Did you know why our service is hands down outstanding in inhalation toxicology in vitro?

Our commitment to exceeding customer expectations is embodied in our “V-CARE Service Promise”. At the heart of our mission, the […]

February 11, 2024

Quantitative Modeling of In Vitro Data Using an Adverse Outcome Pathway for the Risk Assessment of Decreased Lung Function in Humans

https://doi.org/10.1016/j.toxlet.2024.02.001 Alain Sewer, Marja Talikka , Florian Calvino-Martin, Karsta Luettich, Anita IskandarPMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland Highlights […]

February 9, 2024

A Novel Bionebulizer Approach to Study the Effects of Natural Mineral Water on a 3D In Vitro Nasal Model from Allergic Rhinitis Patients

https://doi.org/10.3390/biomedicines12020408 Joana Viegas 1, Elsa M. Cardoso 1,2, Lucile Bonneau 1, Ana Filipa Esteves 1, Catarina L. Ferreira 1,3, Gilberto […]

February 5, 2024

In vitro neurotoxicity of particles from diesel and biodiesel fueled engines following direct and simulated inhalation exposure

https://doi.org/10.1016/j.envint.2024.108481 Lora-Sophie Gerber a b, Dirk C.A. de Leijer a, Andrea Rujas Arranz a, Jonas M.M.L. Lehmann a b, Meike […]

February 2, 2024

Air/Liquid Interface Special Session at European Aerosol Conference 2024

August 25th–30th in Tampere, Finland. An excellent opportunity to discuss ALI exposures. Session title: “Toxicity of Aerosols: Exploring Air-Liquid Interface […]

January 20, 2024

Acute exposure to seasonal PM2.5 induces toxicological responses in A549 cells cultured at the air-liquid interface mediated by oxidative stress and endoplasmic reticulum stress

DOI: 10.1016/j.envres.2024.118283 Wankang Chen 1, Pengxiang Ge 1, Zhenyu Lu 1, Xiaoming Liu 1, Maoyu Cao 2, Zhansheng Yan 1, […]

January 19, 2024

Did you know why we use stainless steel for our exposure systems as much as we can?

Medical grade stainless steel, particularly “V4A”, is our preferred material choice for in vitro exposure systems. It is inert, exhibits […]

January 18, 2024

Comparing the Toxicological Responses of Pulmonary Air–Liquid Interface Models upon Exposure to Differentially Treated Carbon Fibers

https://doi.org/10.3390/ijms24031927 Alexandra Friesen 1, Susanne Fritsch-Decker 2, Sonja Mülhopt 3, Caroline Quarz 1, Jonathan Mahl 3, Werner Baumann 3, Manuela […]

January 15, 2024

Product News 01/2024

See our new VITROCELL® 12/12 PLUS for 12- or 24-well sized inserts. This Exposure System has been specifically designed and […]

December 30, 2023

The use of a complex tetra-culture alveolar model to study the biological effects induced by gold nanoparticles with different physicochemical properties

https://doi.org/10.1016/j.etap.2023.104353 Melissa Saibene a b, Tommaso Serchi a, Patrizia Bonfanti b, Anita Colombo b, Inge Nelissen c, Rashi Halder e, […]

December 26, 2023

Ultrafine Particles Issued from Gasoline-Fuels and Biofuel Surrogates Combustion: A Comparative Study of the Physicochemical and In Vitro Toxicological Effects

https://doi.org/10.3390/toxics11010021 Ana Teresa Juárez-Facio 1, Tiphaine Rogez-Florent 1, Clémence Méausoone 1, Clément Castilla 2, Mélanie Mignot 2, Christine Devouge-Boyer 2, […]

December 25, 2023

The Cytotoxic Effects of Fine Particulate Matter (PM2.5) from Different Sources at the Air-Liquid Interface Exposure on A549 Cells

DOI: 10.3390/toxics12010021 Zhansheng Yan 1, Pengxiang Ge 1, Zhenyu Lu 1, Xiaoming Liu 1, Maoyu Cao 2, Wankang Chen 1, […]

December 21, 2023

VITROCELL at the Workshop “Aerosol and Health” of The Hong Kong Polytechnic University, Universität Rostock and Helmholtz Munich on 06 December 2023 in Rostock

++++++++++ REVIEW: The one day meeting summarized the current work by the research groups of and The latest technologies in […]

December 21, 2023

VITROCELL at LIVe2024 – 20-21. June 2024

++++++++ REVIEW: LIVe 2024 in Nice/France was very lively It was great to meet so many VITROCELL users and interested […]

December 21, 2023

2024 User Group Meeting

We wish to invite you to participate in our User Group Meeting 2024, an excellent opportunity to discuss our latest […]

December 15, 2023

Validation of the VITROCELL Mammalian 48 Exposure Module Using In Vitro Cytotoxicity via the Neutral Red Uptake Assay in Chinese Hamster Ovary Cells Following Exposure to Whole Smoke from Combustible Cigarettes

https://doi.org/10.1089/aivt.2023.0013 Brian M. Keyser1, Robert Leverette1, Michael Hollings2, Emma Rothwell2, Randy A. Weidman1, Carlton J. Bequette1, and Kristen Jordan11Scientiﬁc & […]

November 10, 2023

In vitro lung cell exposure at the air-liquid interface shows significant increase in publications.

Indicating a shift from animal testing towards alternative methods. Sonja Mülhopt from our cooperation partner, the Karlsruhe Institute of Technology […]

October 29, 2023

Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface

https://doi.org/10.1016/j.fct.2023.114157 T. Ruth a, J. Daniel b, A. Konig a, R. Trittler c, M. Garcia-Kaufer aa Institute for Infection Prevention […]

October 20, 2023

Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model

https://doi.org/10.1186/s12989-023-00550-w Gerrit Bredeck1, Jochen Dobner1, Burkhard Stahlmecke2, Khanneh Wadinga Fomba3, Hartmut Herrmann3, Andrea Rossi1 and Roel P. F. Schins11IUF – […]

October 10, 2023

Impact of Electronic Cigarettes, Heated Tobacco Products and Conventional Cigarettes on the Generation of Oxidative Stress and Genetic and Epigenetic Lesions in Human Bronchial Epithelial BEAS-2B Cells

https://doi.org/10.3390/toxics11100847 Gianni Zarcone , Marie Lenski , Thomas Martinez, Smaïl Talahari, Ophélie Simonin, Guillaume Garçon, Delphine Allorge, Fabrice Nesslany, Jean-Marc […]

October 8, 2023

In vitro micronucleus in V79 cells using MicroFlow® – Treatment at the air liquid interface with aerosol from three different nicotine containing products

CORESTA SSPT, October 8-12, 2023, Cancun, Mexico Emma Rothwell, Gina Smith, Sophie Martin and Michael Hollings;Labcorp Early Development Laboratories Ltd., […]

October 8, 2023

In vitro cytotoxicity and mechanistic insight from MucilAir™ and SmallAir™ tissues exposed to cigarette smoke and next-generation products

CORESTA SSPT, October 8-12, 2023, Cancun, Mexico Hollings, M1; Rothwell E1; Martin S1; Daunt, A1; Freiberg, G2; Bedford, R1;Labcorp Early […]

October 8, 2023

Validation of the Vitrocell® HTP 2.0+ 12-well mammalian module for assessing cigarettes, ENDS and eHTPs: Evaluation of dilution airflow, dose resolution and dose repeatability

CORESTA SSPT, October 8-12, 2023, Cancun, Mexico Adam Seymour, Emma Rothwell, Sophie Martin and Michael Hollings;Labcorp Early Development Laboratories Ltd., […]

September 28, 2023

A multi-organ, lung-derived inflammatory response following in vitro airway exposure to cigarette smoke and next-generation nicotine delivery products

https://doi.org/10.1016/j.toxlet.2023.09.010 R. Bedford a, G. Smith a, E. Rothwell a, S. Martin a, R. Medhane a, D. Casentieri a, A. […]

September 25, 2023

VITROCELL at the CORESTA Conference of the Smoke Science and Product Technology Sub-Groups (SSPT2023), 08-12 October 2023

++++++++++ REVIEW: Sunrise for NAMs NAMs (New Approach Methods) are in vitro and in silico or computational-based methodologies in toxicology […]

September 14, 2023

VITROCELL with Cloud Alpha and PowderX at the 57th Congress of the European Societies of Toxicology (EUROTOX), September 10-13, 2023

++++++++++ REVIEW: We had a fantastic time at EUROTOX 2023! VITROCELL displayed the latest Cloud Alpha Devices: Cloud Alpha 12, […]

September 7, 2023

Filling the gaps: A lung-on-chip for R&D and preclinical studies

G. Raggi1, Lea de Maddalena1, Laurène Froment1, Nicole Albrecher1, Arunima Sengupta2,3, Andreas Hugi1, Léa Todeschini1, Janick D. Stucki1, and Nina […]

September 1, 2023

VITROCELL with Cloud Alpha AX12 and Cloud Alpha 12 at the 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12), August 27-31, 2023

++++++++++ Review: We had a great time at WC12! We send a cordial thank you to Dr. Nina Hobi from […]

September 1, 2023

VITROCELL with Cloud Alpha and PowderX at the 24th ISAM Congress, August 26-30, 2023

++++++++++ REVIEW: We had a great time at ISAM 2023! VITROCELL showcased the latest Cloud Alpha Devices: Cloud Alpha 12, […]

August 31, 2023

Product News 08/2023: New VITROCELL® 96-well HTS

The VITROCELL® 96 Exposure System has been specifically designed and engineered to facilitate the research of human cell cultures in […]

August 26, 2023

Monitoring diesel exhaust particles deposition on lung cells in vitro by lock-in thermography

ISAM Congress 2023 – August 26-30, Saarbrücken, Germany Ruiwen He a, Olivier Schaub c, Christoph Geers c, Gowsinth Gunasingam a, […]

August 24, 2023

Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents

https://doi.org/10.1016/j.envint.2023.108169 Marco Dilger a,b, Olivier Armant b,c, Larissa Ramme a,b, Sonja Mülhopt a,d, Sean C. Sapcariu a,e, Christoph Schlager a,d, […]

July 4, 2023

Aerosol exposure to lung-on-chip with the VITROCELL Cloud Alpha AlveoliX AX12 at 2nd MPS World Summit, June 26-30

The “2023 World Summit for Microphysiological Systems” (MPS) had a record attendence with over 1,200 participants from all over the […]

June 30, 2023

A breathing lung-on-chip model of alveolar inflammation illustrating human drug response

Poster MPS Berlin 2023 Clémentine Richter1,2, Patrick Carius1,2, Daria Harig1,2, Nuria Roldan3, Janick Stucki3, Nina Hobi3, Tobias Krebs4, Brigitta Loretz1, […]

June 26, 2023

Product News 06/2023: Exposure of Lung Cells to Liquid Aerosols at the Air/Liquid Interface: New VITROCELL® Cloud Alpha TRIO

Good Things Come in Threes: This latest member of the Cloud Alpha family features the delivery of three different aerosol […]

June 16, 2023

VITROCELL® V-CARE Service

At VITROCELL®, exceptional customer service is the foundation of our customer relationships. We have now taken a step further by […]

May 18, 2023

Transferability and reproducibility of exposed air-liquid interface co-culture lung models

https://doi.org/10.1016/j.impact.2023.100466 Hedwig M. Braakhuis a, Eric R. Gremmer a, Anne Bannuscher b, Barbara Drasler b, Sandeep Keshavan b, Barbara Rothen-Rutishauser […]

May 10, 2023

2nd MPS World Summit, Booth 53, June 26-30, 2023

The MPS World Summit, organized by the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) and EUROoCS, with the […]

May 10, 2023

Method development of a waterpipe aerosol exposure system for in vitro testing using 3D reconstructed human airway tissue

Jeremie Gafner , Christelle Lamboley , Louise NeilsonJT International SA, Scientific & Regulatory Affairs, Geneva, Switzerland The study’s objective was […]

April 6, 2023

10th NanOEH Conference

In 2023, two internationally renowned conferences, Inhaled Particles and NanOEH are coming together to disseminate the current knowledge and understanding […]

March 20, 2023

Product News 03/2023

Please see our latest product improvements and developments, such as the 24/48 Exposure System, the PowderX for dry powder exposure […]

March 20, 2023

New Products at VITROCELL® User Group Meeting 2023

After a long break we finally could meet again – a lot of innovation has happened since our 2019 meeting […]

March 19, 2023

Human cell-based in vitro systems to assess respiratory toxicity: A case study using silanes

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Monita Sharma1, Andreas O. Stucki1, Sandra Verstraelen2, An […]

March 19, 2023

Cytotoxicity Assessment of Heated Tobacco Product and Combustible Cigarette Aerosols Utilizing Whole Aerosol Exposure in the Neutral Red Uptake Assay

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Robert Leverette1, Thomas Shutsky1, Rebecca Payne2, Kristen Jordan1 […]

March 19, 2023

Nrf2 Responses in a 3D Human Airway Model Exposed to Whole Aerosol from Combustible Cigarettes or Heated Tobacco Products

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Brian M. Keyser1, John Wertman1, Michael Hollings2, Kristen […]

March 19, 2023

Non-Combustible Next Generation Products induce lower toxiscity than Combustible Tobacco in an Alveolar-Immune coculture model

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Matthew Stevenson1, Ewelina Hoffmann2, Abigail Martin2, Edgar Trelles […]

March 19, 2023

Non-combustible Next Generation Products induce lower biological activity than combustible tobacco on a human cardiovascular model on-a-chip

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Fiona Chapman1, Luuk de Haan2, Linda Gijzen2, Edgar […]

March 19, 2023

Method Development to Establish and Characterize an Air Liquid Interface (ALI) Exposure System Using Perfluorooctanoic Acid (PFOA) Liquid Aerosol

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Amit Gupta, Bob Moyer, Stephanie Pearson, William Puerner, […]

March 19, 2023

Filling the gaps: translating lung in vitro toxicology

SOT 62nd Annual Meeting and ToxExpo, March 19-23 2023, Nashville, Tennessee, USA Nuria Roldan1, G. Raggi1, Lea de Maddalena1, Arunima […]

March 16, 2023

Biological impact of sequential exposures to allergens and ultrafine particle-rich combustion aerosol on human bronchial epithelial BEAS-2B cells at the air liquid interface

doi: 10.1002/jat.4458 Elias Josef Zimmermann 1 2, Joana Candeias 3, Nadine Gawlitta 1, Christoph Bisig 1, Stephanie Binder 1 2, […]

March 15, 2023

Development and Characterization of a 96-Well Exposure System for Safety Assessment of Nanomaterials

DOI: 10.1002/smll.202207207 Yvonne Kohl1, Michelle Müller1, Marielle Fink2, Marc Mamier2, Siegfried Fürtauer3, Roland Drexel4, Christine Herrmann5, Stephan Dähnhardt-Pfeiffer6, Ramona Hornberger3, […]

March 11, 2023

Evaluation of the cytotoxic and genotoxic potential of printer toner particles in a 3D air-liquid interface, primary cell-based nasal tissue model

DOI: 10.1002/jat.3038 Till Jasper Meyer a, Nursen Tekin a, Peter Hense b, Totta Ehret-Kasemo a, Nina Lodes c, Manuel Stöth […]

March 9, 2023

Society of Toxicology’s 62nd Annual Meeting and ToxExpo

Taking place in Nashville, Tennessee, the SOT 62nd Annual Meeting and ToxExpo will feature more than 70 Featured and Scientific […]

March 6, 2023

A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip

doi: 10.3389/fphar.2023.1114739 Arunima Sengupta 1, Aurélien Dorn 1,2, Mohammad Jamshidi 1, Magali Schwob1, Widad Hassan 1, Lea Lara De Maddalena […]

February 15, 2023

Processing of carbon-reinforced construction materials releases PM2.5 inducing inflammation and (secondary) genotoxicity in human lung epithelial cells and fibroblasts

https://doi.org/10.1016/j.etap.2023.104079 Jana Pantzke a,b, Arne Koch a, Elias J. Zimmermann a,b, Narges Rastak b, Svenja Offer a,b, Christoph Bisig b, […]

January 19, 2023

Different Sensitivity of Advanced Bronchial and Alveolar Mono- and Coculture Models for Hazard Assessment of Nanomaterials

DOI: 10.3390/nano13030407 Elisabeth Elje 1,2,Espen Mariussen 1,3,Erin McFadden 1,Maria Dusinska 1 and Elise Rundén-Pran 1,1 Health Effects Laboratory, Department for […]

January 19, 2023

2023 User Group Meeting

We wish to invite you to participate at our User Group Meeting 2023, an excellent opportunity to discuss our latest […]

January 18, 2023

Comparing the Toxicological Responses of Pulmonary Air-Liquid Interface Models upon Exposure to Differentially Treated Carbon Fibers

doi: 10.3390/ijms24031927 Alexandra Friesen 1, Susanne Fritsch-Decker 2, Sonja Mülhopt 3, Caroline Quarz 1, Jonathan Mahl 3, Werner Baumann 3, […]

December 14, 2022

Carbonyl Profiles of Electronic Nicotine Delivery System (ENDS) Aerosols Reflect Both the Chemical Composition and the Numbers of E-Liquid Ingredients–Focus on the In Vitro Toxicity of Strawberry and Vanilla Flavors

https://doi.org/10.3390/ijerph192416774 Alexandra Noël and Arpita GhoshDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA […]

November 18, 2022

Rescue of Ciliary Function in Cell-based Primary Ciliary Dyskinesia Models using Nebulized, LNP-formulated mRNA

Rumpa B. Bhattacharjee1, Mirko Hennig1, Daniella Ishimaru1, David Liston1, Jackson K. Eby2, Christian C. Corona1, Ishita Agarwal1 Jade E. Casillas1, […]

November 14, 2022

An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials

https://doi.org/10.1016/j.impact.2022.100439 Anne Bannuscher a, Otmar Schmid b,c, Barbara Drasler a, Alain Rohrbasser a, Hedwig M. Braakhuis d, Kirsty Meldrum e, Edwin […]

November 3, 2022

Characterization of smoke and aerosol deliveries from combustible cigarettes, heated tobacco products and electronic nicotine delivery systems in the Vitrocell® Mammalian 6/48 exposure module

https://doi.org/10.1016/j.toxrep.2022.11.001 Brian M. Keyser1, Robert Leverette1, Michael Hollings2, Adam Seymour2, Randy A. Weidman3, Carlton J. Bequette3, Kristen Jordan1 1 RAI […]

October 28, 2022

ESTIV 2022 – International Congress of the European Society of Toxicology In Vitro

VITROCELL will participate in the 21st International Congress of the European Society of Toxicology In Vitro (ESTIV 2022), held […]

October 27, 2022

VITROCELL® sQCM 12: Data Interpretation

The Quartz Crystal Microbalance is a powerful tool for dosimetry in VITROCELL Exposure Systems. However, interpreting live-data from a sQCM […]

October 13, 2022

Toxicological impact of organic ultrafine particles (UFPs) in human bronchial epithelial BEAS-2B cells at air-liquid interface

https://doi.org/10.1016/j.tiv.2021.105258 A. T. Juarez Facio1, J. Yon2, C. Corbière1, T. Rogez-Florent1, C. Castilla3, H. Lavanant3, M. Mignot3, C. Devouge-Boyer3, C. […]

September 30, 2022

NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene

https://doi.org/10.1016/j.tox.2022.153340 Marjory Moreau, Jeff Fisher, Melvin E. Andersen, Asayah Barnwell, Sage Corzine, Aarati Ranade, Patrick D. McMullen, Scott D. Slattery […]

September 30, 2022

Dynamic Fluid Flow Exacerbates the (Pro-)Inflammatory Effects of Aerosolised Engineered Nanomaterials In Vitro

https://doi.org/10.3390/nano12193431 Kirsty Meldrum, Joana A. Moura, Shareen H. Doak and Martin J. D. Clift In Vitro Toxicology Group, Swansea University […]

September 26, 2022

Product News 06-9/2022

For fully automated and repeated row-by-row exposure of 12-, 24- and 96-well sized cell culture inserts. Testing of up to […]

September 9, 2022

ICT 2022 – International Congress of Toxicology

After an intensive preparation period, it is with great pleasure that the Dutch Society of Toxicology (NVT) is welcoming […]

August 22, 2022

Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways

https://doi.org/10.1038/s41598-022-18098-8 Torben Stermann1, Thach Nguyen1, Burkhard Stahlmecke2, Ana Maria Todea2, Selina Woeste1, Inken Hacheney1, Jean Krutmann1,3, Klaus Unfried1, Roel P. […]

July 29, 2022

Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures

https://doi.org/10.3390/nano12152609 Laura Maria Azzurra Camassa 1, Elisabeth Elje 2,3, Espen Mariussen 2,4, Eleonora Marta Longhin 2, Maria Dusinska 2, Shan […]

June 21, 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells

https://doi.org/10.1016/j.envint.2022.107366 Michal Pardoa, Svenja Offerbc, Elena Hartnerbc, Sebastiano Di Bucchianicob, Christoph Bisigb, Stefanie Bauerb, Jana Pantzkebc, Elias J. Zimmermannbc, XinCaobc, […]

June 15, 2022

Characterization of Aerosol Deliveries from Combustible Cigarettes, Heated Tobacco Products, and Electronic Nicotine Delivery Systems Using the Vitrocell Ames 48

DOI: 10.1089/aivt.2022.0001 Brian M. Keyser,1 Robert Leverette,1 Michael Hollings,2 Adam Seymour,2 Randy J. Weidman,3 Carlton J. Bequette,3 and Kristen Jordan1 […]

June 1, 2022

Product News 05-4/2022

For cell culture exposure to smallest quantities of dry powders The VITROCELL® PowderX allows for aerosolisation of small quantities of […]

April 15, 2022

Aerosol–Cell Exposure System Applied to Semi-Adherent Cells for Aerosolization of Lung Surfactant and Nanoparticles Followed by High Quality RNA Extraction

https://doi.org/10.3390/nano12081362 Mélanie M. Leroux 1 , Romain Hocquel 1, Kevin Bourge 1 , Boštjan Kokot 2 , Hana Kokot 2 […]

April 11, 2022

Product News 04-3/2022

Aerosol exposure for breathing AX Lung-on-Chip The VITROCELL® Cloud Alpha AX12 is our newest innovation in the Cloud family and […]

April 6, 2022

Product News 04-2/2022

Manual smoking machine with high tech features The VC 1 smoking machine is used for a controlled aerosol generation of […]

April 4, 2022

Product News 04-1/2022

Increase of nebulizations and evacuation of residual gaseous compounds A typical Cloud exposure allows 3 consecutive nebulizations. The PowerVent option […]

March 27, 2022

Nrf2 Responses of Commercial Cigarette Whole Smoke and Aerosol from Six Electronic Nicotine Delivery Systems (ENDS) in a 3D Human Airway Model

Brian M. Keyser1, John Wertman1, Michael Hollings2, Robert Bedford2, and Kristen Jordan1 1 Scientific & Regulatory Affairs, RAI Services Company, […]

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