VITROCELL® PowderX

For cell culture exposure to smallest ­quantities of dry powders


PowderX allows for aerosolisation of small quantities of dry powders (1-100 mg) and particle deposition on cells cultured on 12- or 24-well sized inserts.

The system features biological barrier integration and continuous sampling from the basolateral compartment.

Working Principle

  • Powder sample is placed in quick-lock loading system.
  • Expansion chamber and base module are tightly sealed by touchscreen operation.
  • Powder sample is aerosolized under high pressure to break up agglomerates for homogeneous dispersion in the expansion chamber.
  • Powder sample settles on cell cultures.

More about VITROCELL PowderX

Base Module

The base module is prepared for continuous or time-based sampling from the media compartment.

Inserts

Base module houses 12- (left) or 24-well sized inserts (right).
All commercial brands are supported.

Loading System

Quick-lock loading system open (left) and closed (right).

Expansion Chamber

Medium size expansion chamber – standby (left) and sealed (right).

sQCM 12 Dry Powder Kit
for inline Dose Monitoring in PowderX

The assessment of dry particles is a significant challenge in toxicology and related fields. Particularly in nanoparticle research, the deposition of dry particles onto surfaces such as quartz crystal sensors (QCM) often results in irregular deposition patterns and poor surface bonding, leading to unreliable data.

The sQCM 12 sensor, developed by VITROCELL®, offers a high-sensitivity platform capable of detecting mass changes in nanogram ranges. However, reliable measurement with a QCM requires a rigid layer of deposited material. The VITROCELL® sQCM 12 Dry Powder Kit provides a solution for a wide range of powder materials.

Discover more details in 3D-interaction

Features

  • Easy handling
  • Only small quantities of powder needed (5–100 mg)
  • No external airflow required
  • Exposure time < 30 minutes
  • Optional continuous media supply or media sampling
  • Optional magnetic stirring for media compartment
  • Intuitive user experience with touchscreen operation

Videos

PowderX Function Principle

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VITROCELL® PowderX

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